Research
The MOBIL programme consists of five Centres of Excellence at the Faculty of Science and Technology working in the field of molecular biosciences. The centres have been established with the support from the Danish National Research Foundation.
- CARB – Centre for Carbohydrate Recognition and Signalling
- CDNA – Centre for DNA Nanotechnology
- inSPIN – Centre for Insoluble Protein Structures
- mRNP – Centre for mRNP Biogenesis and Metabolism
- PUMPKIN – Centre for Membrane Pumps in Cells and Disease
See description for each centre below.
CDNA – Centre for DNA Nanotechnology
CDNA explores fundamental aspects of DNA as a programmable tool for directing the assembly of molecules and materials into nanoarchitectures and functional structures.
inSPIN – Centre for Insoluble Protein Structures
Our aim is to develop and apply new methods for the analysis of proteins in insoluble biological structures, including membrane proteins, fibrillating proteins and extracellular matrix proteins. These proteins constitute about half of the proteome in any cell and are involved in essential biological functions – this be for life or disease – but only little is known about them at a detailed level.
CARB – Centre for Carbohydrate Recognition and Signalling
The research at CARB aims to understand the interactions between cells and organisms by investigating the role of polysaccharides exposed on cell surfaces, and polysaccharide signal molecules secreted as part of the interaction between organisms.
mRNP – Centre for mRNP Biogenesis and Metabolism
The centre for mRNP Biogenesis and Metabolism studies the crosstalk between transcriptional and post-transcriptional processes, which establishes a network of interdependencies that ultimately regulate gene expression. Our focus is on structure/function relationships of mRNP formation and its quality control as well as the occurrence, and putative function, of non-coding RNA transcription.
PUMPKIN – Centre for Membrane Pumps in Cells and Disease
PUMPKIN studies the structure and function of P-type ATPase pumps. These transporters serve a wide range of functions such as maintaining the cation gradients across membranes that energise other transport and signalling schemes in the cell, neurotransmission, uptake of neurotransmitters and calcium-mediated signalling. They pump acid into the stomach and regulate the osmotic balances that drive the water flow in the body. The family of P-type pumps encompasses several lipid flippases which are critical for vesicle-mediated transport schemes such as in the secretory pathways with endocytosis and exocytosis, but for which we still know very little.